A documentary made up of nine separate segments on the topic of drug addiction. Segments include: Saturday Night in a Dallas ER, by Jon Alpert; A Mothers Desperation, by Susan Froemke and Albert Maysles; The Science of Relapse, by Eugene Jarecki and Susan Froemke; The Adolescent Addict, by Kate Davis and David Heilbroner; Brain Imaging, by Liz Garbus and Rory Kennedy; Opiate Addiction: A New Medication, by D.A. Pennebaker and Chris Hegedus; Topiramate: A Clinical Trial for Alcoholism, by Alan and Susan Raymond; Steamfitters Local Union 638, by Barbara Kopple; and Insurance Woes, by Susan Froemke.