Young lesbian parents Shareen and Claire are raising their 5-year-old daughter Honey in a converted garage on Staten Island. Shareen salvages refuse with her pickup truck while Claire waits tables at the hip Naga Saki restaurant in Manhattan, caught up in a global exchange of industrial waste via contaminated sushi. As a ghost barge bearing nuclear refuse circles the planet in search of a willing port, household pets begin to glow ominously, then disappear; and people start speaking in tongues. The crisis escalates when a multinational corporation is implicated, the couples daughter Honey mysteriously vanishes, and a group of young New Yorkers strike back in an unlikely alliance with activists in the developing world.