Among the finalists for Centerfold Of The Year are Angel and her spiteful rival Betty. However, no one is aware of Angels involvement in a secret medical beauty enhancement program headed by Dr. Lindstrom. Desperate to win, Angel overdoses on Lindstroms formula, with disastrous results. Soon she has grown to monstrous but shapely proportions, causing all sorts of complications, the most dangerous being Bettys jealousy of Angels new-found attention. Betty discovers Angels secret and takes the formula herself, causing her to grow into an equally gorgeous giant. As the girls battle it out on Hollywood Blvd., Dr. Lindstrom races to find an antidote.