In the small town of Stone Cove, Maine, sheriffs deputy Dwayne Hopper is on the night-shift. He discovers Ronald Perkins in a holding cell. Hes a local pharmacist and suspect in the disappearance of fourteen children over the past ten years, including Hoppers young son. Interrogating Perkins, Hopper learns that the mad pharmacist has built an army of brainwashed people. Investigating, Hopper and the police unwittingly unleash his followers on the small town and a night of terror begins as the super-strong, zombie-like warriors wreak havoc with only one thing on their minds: Kill for Mr. Perkins.